Morehouse, Nicholas J.Clark, Trevor N.Kerr, Russell G.Johnson, John A.Gray, Christopher A.2024-07-172024-07-172023-06-021520-6025https://unbscholar.lib.unb.ca/handle/1882/38042Punctaporonins T (1) and U (2), new caryophyllene sesquiterpenes, were isolated with three known punctaporonins, A (3), B (4), and C (5), from the endophytic fungus Chaetomium globosum (TC2-041). The structures and relative configurations of punctaporonins T and U were elucidated based on a combination of HRESIMS, 1D/2D NMR spectroscopic analysis, and X-ray diffraction analysis whilst their absolute configuration is presumed to be consistent with the co-isolated 3–5 on biogenetic arguments. Compound 1 showed weak inhibitory activity against both Mycobacterium tuberculosis and Staphylococcus aureus.enhttp://purl.org/coar/access_right/c_abf2journal articleChemistry