Investigation of antimicrobial activity of Canadian medicinal plant extracts

dc.contributor.advisorGray, Christopher
dc.contributor.advisorJohnson, John
dc.contributor.authorDao, Khoi Thien
dc.date.accessioned2023-03-02T23:42:47Z
dc.date.available2023-03-02T23:42:47Z
dc.date.issued2018
dc.description.abstractMethanolic extracts of seven Canadian medicinal plants were investigated for antimicrobial activity against a Gram-positive bacterium (Staphylococcus aureus), a Gram-negative bacterium (Pseudomonas aeruginosa), and a fungal organism (Candida albicans). Chamerion angustifolium extract was highly bioactive against S. aureus and P. aeruginosa; Crataegus sp. extract was moderately bioactive against S. aureus, but had a low bioactivity against C. albicans. The extract from Betula papyrifera had a low bioactive against both S. aureus and C. albicans. The active constituents of C. angustifolium, Crataegus sp., and B. papyrifera were detected via separation using two-dimensional thin layer chromatography followed by testing against S. aureus using bioautography. This is the first study to report antimicrobial activity of Crataegus sp. native to Canada and first study to find the antimicrobial constituents of C. angustifolium and B. papyrifera.
dc.description.copyrightThis work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit: http://creativecommons.org/licenses/by/4.0/ or send a letter to Creative Commons, PO Box 1866, Mountain View, CA 94042, USA.
dc.formattext/xml
dc.format.extentx, 39 pages
dc.format.mediumelectronic
dc.identifier.urihttps://unbscholar.lib.unb.ca/handle/1882/22307
dc.language.isoen_CA
dc.publisherUniversity of New Brunswick
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subject.disciplineBiology
dc.titleInvestigation of antimicrobial activity of Canadian medicinal plant extracts
dc.typebachelor thesis
thesis.degree.disciplineBiology
thesis.degree.fullnameBachelor of Science with Honours in Biology-Psychology
thesis.degree.grantorUniversity of New Brunswick
thesis.degree.levelundergraduate
thesis.degree.nameB.Sc.

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