The impact of acute resistance training on irisin in younger and older adults living with overweight or obesity
Loading...
Files
Date
2018
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
University of New Brunswick
Abstract
BACKGROUND: Exercise is a cornerstone for the prevention and management of
overweight and/or obesity (OW/OB). Studies suggest that exercise-induced irisin impacts
metabolism and health. However, no study has quantified the impact of biological aging
on resistance training (RT)-induced increase in irisin.
OBJECTIVES: The purpose of this study was to determine whether irisin concentration
would increase during an acute RT bout and to compare irisin release between younger
and older adults living with OW/OB.
METHODS: Adults aged between 19-35 (25.9 ± 5.0; n=15) and 60-80 years old (67.7 ±
4.1; n=14) living with OW/OB participated in this study. The primary exposure variable
was an acute bout of RT, which consisted of 3 sets of 12-15 repetitions at 65-70% of 1-
Repetition Maximum and 3 minutes each of squats and step-box. The primary outcome
measure was the concentration of irisin quantified by ELISA before, during, and after the
acute bout of RT.
RESULTS: Significant differences were observed between younger and older adults in
waist circumference, body fat, fitness levels, and muscle strength (all p < 0.05). However,
no differences were observed in physical activity levels (young: 46.0 ± 45.5 vs. older adults:
31.2 ± 30.8 min.; p > 0.05) nor body mass index (young: 28.6 ± 4.0 vs. older adults: 29.8 ±
4.7 kg/m2; p > 0.05). Repeated measures analyses showed no effect of time on irisin during
acute RT, and no interaction effect between age and time (p > 0.05).
CONCLUSIONS: The results of the current study suggest that there is no impact of
biological aging on the acute release of irisin during RT in individuals living with
OW/OB. Further studies are needed to elucidate the irisin response to acute exercise with
different modalities/intensities of exercise.