Mouse embryonic fibroblasts accumulate differentially on titanium surfaces treated with nanosecond laser pulses

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dc.contributor.authorRadmanesh, Mitra
dc.contributor.authorEktasabi, Amin M.
dc.contributor.authorWyatt, Rachael A.
dc.contributor.authorCrawford, Bryan D.
dc.contributor.authorKiani, Amirkianoosh
dc.date.accessioned2023-03-02T23:44:06Z
dc.date.available2023-03-02T23:44:06Z
dc.date.issued2016
dc.description.abstractBiomaterial engineering, specifically in bone implant and osseointegration, is currently facing a critical challenge regarding the response of cells to foreign objects and general biocompatibility of the materials used in the production of these implants. Using the developing technology of the laser surface treatment, this study investigates the effects of the laser repetition rate (frequency) on cell distribution across the surface of the titanium substrates. The main objective of this research is building a fundamental understanding of how cells interact with treated titanium and how different treatments affect cell accumulation. Cells respond differently to surfaces treated with different frequency lasers. The results of this research identify the influence of frequency on surface topography properties and oxidation of titanium, and their subsequent effects on the pattern of cell accumulation on its surface. Despite increased oxidation in laser-treated regions, the authors observe that fibroblast cells prefer untreated titanium to laser-treated regions, except the regions treated with 25 kHz pulses, which become preferentially colonized after 72 h.
dc.description.copyrighthttp://www.sherpa.ac.uk/romeo/issn/1934-8630/
dc.identifier.urihttps://unbscholar.lib.unb.ca/handle/1882/22344
dc.identifier.urlhttp://scitation.aip.org/content/avs/journal/bip/11/3/10.1116/1.4962066
dc.language.isoEnglish
dc.publisherAVS: Science & Technology of Materials, Interfaces, and Processing
dc.relation.hasversion10.1116/1.4962066
dc.rightshttp://purl.org/coar/access_right/c_abf2
dc.subject.disciplineBiology
dc.titleMouse embryonic fibroblasts accumulate differentially on titanium surfaces treated with nanosecond laser pulses
dc.typejournal article
oaire.citation.issue3
oaire.citation.titleBiointerphases
oaire.citation.volume11

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